Manufacturer: Focus Biomolecules
NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 µM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.
CAS Number: 3030588-01-0
Manufacturer Part Number/SKU: 10-4134-5mg-EA
Tags: Focus Biomolecules