NLG919, IDO pathway inhibitor, 5mg, CAS# 1402836-58-1
$60.00
1-Cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol Purity: 985 by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4564-5mg-EA
NLG919, IDO pathway inhibitor, 5mg, CAS# 1402836-58-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsNLG919 (1402836-58-1) is a potent IDO-pathway inhibitor (Ki = 7nM; EC50 = 75nM).1 It synergizes with chemo-radiation therapy to promote T cell dependent complement deposition in a murine model of glioblastoma.2 In combination with paclitaxel in a mouse B16-F10 melanoma model, NLG919 increased the percentage of CD3+, CD8+, and CD4+ T cells and secretion of IFN-γ and interleukin-2 while decreasing the percentage of CD4+CD25+ regulatory T cells.3
CAS Number: 1402836-58-1
Manufacturer Part Number/SKU: 10-4564-5mg-EA
Tags: Focus Biomolecules