Nitazoxanide, Antiviral and antiparasitic agent, 10mg, CAS# 55981-09-4

Nitazoxanide is a clinically relevant antiparasitic agent.1It has since been repurposed as a broad-spectrum antiviral agent that is active against many RNA and DNA viruses including influenza, Hepatitis B and C, RSV, coronavirus, dengue and others.2 Its antiparasitic activity is believed to be due to inhibition of pyruvate:ferredoxin/flavodoxin oxidoreductases.3 Antiviral activity involves activation of protein kinase activated by double-stranded RNA (PKR) leading to phosphorylation of eukaryotic initiation factor 2 alpha (eIF2α).4 Nitazoxanide has also been found to inhibit Wnt signaling independent of adenomatous polyposis coli (APC) - it targets peptidyl arginine deiminase 2 (PAD2) resulting in increased citrullination of β-catenin.5

CAS Number: 55981-09-04

Manufacturer Part Number/SKU: 10-4633-10mg-EA

Tags: Focus Biomolecules