Nintedanib, VEGFR, PDGFR and FGFR kinase inhibitor, 10mg, CAS# 656247-17-5
$45.00
Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3320-10mg-EA
Nintedanib, VEGFR, PDGFR and FGFR kinase inhibitor, 10mg, CAS# 656247-17-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsNintedanib is a potent inhibitor of VEGFR, PDGFR, FGFR (IC50 = 13-34 nM for VEGFR, 59-65 nM for PDGFR and 37-108 nM for FGFR subtypes).1 Also inhibits Flt-3, Lck, Lyn and Src (IC50 = 16-156 nM). Inhibits VEGF-stimulated proliferation of HUVECs.1 Inhibits tumor growth in a mouse tumor xenograft model.1 A novel therapeutic agent for treatment of idiopathic pulmonary fibrosis.2,3 Alleviates chronic pancreatitis by inhibiting the activation of pancreatic stellate cells.4
CAS Number: 656247-17-5
Manufacturer Part Number/SKU: 10-3320-10mg-EA
Tags: Focus Biomolecules