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Necrosulfonamide, Necroptosis inhibitor / MLKL inhibitor, 5mg, CAS# 1360614-48-7

$45.00
(2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4860-5mg-EA
Necrosulfonamide, Necroptosis inhibitor / MLKL inhibitor, 5mg, CAS# 1360614-48-7 is available to buy in increments of 1

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Specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5

CAS Number: 1360614-48-7

Manufacturer Part Number/SKU: 10-4860-5mg-EA

Tags: Focus Biomolecules