Necrostatin-1, Necroptosis inhibitor, 10mg, CAS# 4311-88-0
$55.00
5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidazolidinone Purity: 98% by TLC [5% methanol in methylene chloride Purity: Rf = 0.37] NMR Conforms Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1162-10mg-EA
Necrostatin-1, Necroptosis inhibitor, 10mg, CAS# 4311-88-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsNecrostatin-1 is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM).1 It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM).2 It displays a protective effect in a mouse model of ischemic brain injury1, inhibits myocardial cell death and reduces infarct size in various mouse heart models3 and inhibits glutamate-induced oxytosis in HT-22 cells4.
CAS Number: 4311-88-0
Manufacturer Part Number/SKU: 10-1162-10mg-EA
Tags: Focus Biomolecules