Myriocin_ISP-1, Blocks sphingolipid biosynthesis, 25mg, CAS# 35891-70-4

Myriocin_ISP-1, Blocks sphingolipid biosynthesis, 25mg, CAS# 35891-70-4

Nigericin_Na, Induces rapid intracellular acidification,   25mg, CAS# 28643-80-3

Nigericin_Na, Induces rapid intracellular acidification, 25mg, CAS# 28643-80-3

Myriocin (ISP-1), Blocks sphingolipid biosynthesis, 5mg, CAS# 35891-70-4

$58.00
(2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid Purity: >98% Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-2088-5mg-EA
Myriocin (ISP-1), Blocks sphingolipid biosynthesis, 5mg, CAS# 35891-70-4 is available to buy in increments of 1

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Myriocin is a fungal metabolite with potent immunosuppressant activity.1 It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide.2 It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.3

CAS Number: 35891-70-4

Manufacturer Part Number/SKU: 10-2088-5mg-EA

Tags: Focus Biomolecules