Manufacturer: Focus Biomolecules
MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5).1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinson's3,4, Fragile X syndrome5, and addiction6.
CAS Number: 219911-35-0
Manufacturer Part Number/SKU: 10-4007-5mg-EA
Tags: Focus Biomolecules