Monastrol, Kinesin Eg5 and mitosis inhibitor, 5mg, CAS# 254753-54-3
$75.00
1,2,3,4-tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylic acid Purity: ethyl ester Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2629-5mg-EA
Monastrol, Kinesin Eg5 and mitosis inhibitor, 5mg, CAS# 254753-54-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 μM).2 Mimics the effect of amyloid β on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4
CAS Number: 254753-54-3
Manufacturer Part Number/SKU: 10-2629-5mg-EA
Tags: Focus Biomolecules