ML365, Potent and selective K2P3.1 blocker, 25mg, CAS# 947914-18-3
$225.00
2-Methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4658-25mg-EA
ML365, Potent and selective K2P3.1 blocker, 25mg, CAS# 947914-18-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsML365 is a potent (IC50 = 16 nM) and selective (62-fold selective over TASK-3) blocker of the two-pore domain potassium channel K2P3.1 (TASK-1) .1 It also less potently (IC50 = 4.07 µM) blocks the K2P6.1 (TWIK-2) channel resulting in blocking the ATP-induced NLRP3 inflammasome.2 ML365 improved the efficacy of Levetiracetam in chronically epileptic rats.3 It suppressed the release of TNF-α, IL-6, and IL-1ß in an LPS-induced inflammatory model via regulation of NF-kB signaling.4
CAS Number: 947914-18-3
Manufacturer Part Number/SKU: 10-4658-25mg-EA
Tags: Focus Biomolecules