ML277, Potent Kv7.1 activator, 25mg, CAS# 1401242-74-7
$220.00
(2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)(sulfonyl]-2-piperidinecarboxamide Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4074-25mg-EA
ML277, Potent Kv7.1 activator, 25mg, CAS# 1401242-74-7 is available to buy in increments of 1
Product Details
Download Details and SpecificationsML277 is a potent (EC50 = 260 nM) activator of Kv7.1 with selectivity against Kv7.2, Kv7.4, and Kv11.1 (hERG).1 ML277 enhances cardiac delayed rectifier K+ currents (IKs) in human iPSC-derived cardiomyocytes from normal and long QT-interval syndrome afflicted patients suggesting potential therapeutic use in long QT-interval syndrome.2,3 It displayed cardioprotective effects against ischemia in cellular and whole-heart models.4
CAS Number: 1401242-74-7
Manufacturer Part Number/SKU: 10-4074-25mg-EA
Tags: Focus Biomolecules