MK-2206, Potent and selective AKT inhibitor, 25mg, CAS# 1032350-13-2
$190.00
8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one dihydrochloride Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4801-25mg-EA
MK-2206, Potent and selective AKT inhibitor, 25mg, CAS# 1032350-13-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsMK-2206 is a potent and selective allosteric inhibitor of Akt (IC50's: Akt1 = 5 nM, Akt2 = 12 nM, Akt3 = 65 nM) that enhances the in vitro and in vivo antitumor efficacy of several standard chemotherapeutic agents.1 It was able to decrease insulin-stimulated glucose uptake, glycogen synthesis and glycogen synthase activity in rat muscle.2 MK-2206 induced G1-phase cycle arrest and sensitized HepG2 hepatocellular carcinoma cells to TRAIL-induced apoptosis.3
CAS Number: 1032350-13-2
Manufacturer Part Number/SKU: 10-4801-25mg-EA
Tags: Focus Biomolecules