MitoBloCK-6, Mitochondrial import inhibitor, 5mg, CAS# 303215-67-0
$60.00
2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1472-5mg-EA
MitoBloCK-6, Mitochondrial import inhibitor, 5mg, CAS# 303215-67-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibits redox-regulated protein translocation into mitochondria. It attenuates the import of Erv1 substrates by inhibition of Erv1 oxidase activity (the import of Tim23 and AAC was decreased by ~50% at 20 μM). MitoBloCK-6 elucidated an unexpected role for Erv1 in the carrier import pathway, namely transferring substrates from the translocase of the outer membrane complex into the small Tim complexes. It impaired cardiac development in zebrafish embryos and induced apoptosis via the release of cytochrome c in human embryonic stem cells but not differentiated cells1.
CAS Number: 303215-67-0
Manufacturer Part Number/SKU: 10-1472-5mg-EA
Tags: Focus Biomolecules