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Mito-lonidamine, Mitochondria-targeted antiglycolytic agent, 25mg, CAS# 2361564-49-8

$400.00
(10-(1,(2,4-Dichlorobenzyl)-1H-indazole-3-carboxamido)decyl)triphenylphosphonium bromide Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-5492-25mg-EA
Mito-lonidamine, Mitochondria-targeted antiglycolytic agent, 25mg, CAS# 2361564-49-8 is available to buy in increments of 1

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Antiglycolytic drug with limited efficacy.1,2 Mito-lonidamine (2361564-49-8) is lonidamine conjugated to a triphenylphosphonium moiety via a decyl-linker which is an effective mitochondria-targeting group.3 Mito-lonidamine was shown to be100-fold more potent than lonidamine. It is a tumor-selective inhibitor of oxidative phosphorylation inhibiting mitochondrial bioenergetics in lung cancer cells and suppressing lung cancer cell viability, growth, progression and metastasis of lung cancer xenografts in mice.3

CAS Number: 2361564-49-8

Manufacturer Part Number/SKU: 10-5492-25mg-EA

Tags: Focus Biomolecules