Manufacturer: Focus Biomolecules
Mirin is an inhibitor of the Mre11-Rad50-Nbs1(MRN) complex (IC50 = 12 µM for inhibition of ATM activity), part of the MRN-ATM(ataxia-telangiectasia mutated) pathway, an essential pathway for sensing and signaling from DNA double-strand breaks. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
CAS Number: 299953-00-7
Manufacturer Part Number/SKU: 10-1069-25mg-EA
Tags: Focus Biomolecules