MF-438, SCD1 inhibitor, 25mg, CAS# 921605-87-0
$250.00
2-Methyl-5-(6-(4-(2-trifluoromethyl)phenoxy)piperidin-3-yl)-1,3,4-thiadiazole Purity: 98% by HPLC Purity: NMR (Confirms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4558-25mg-EA
MF-438, SCD1 inhibitor, 25mg, CAS# 921605-87-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsMF-438 is a potent inhibitor of stearoyl-CoA desaturase 1 (SCD1) - IC50 = 2.3 nM.1 MF-438 was potent in an in vivo mouse liver PD assay (ED50 between 1 and mg/kg).1 Cancer initiating cells (CSC-like) were shown to much more sensitive to MF-438 inhibition of SCD1 than progenitor and terminally differentiated cancer cells in a lung cancer model.2 MF-438 showed good oral bioavailability and metabolic stability making it an excellent tool for studying the effects of SCD1 in various disease models.
CAS Number: 921605-87-0
Manufacturer Part Number/SKU: 10-4558-25mg-EA
Tags: Focus Biomolecules