MDL-28170, Calpain inhibitor, 25mg, CAS# 88191-84-8
$200.00
N-Benzyloxycarbonylvalylphenylalaninal Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3005-25mg-EA
MDL-28170, Calpain inhibitor, 25mg, CAS# 88191-84-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent and selective cell permeable calpain inhibitor. Inhibits oxidative damage-induced apoptosis in PC12 cells and capsaicin-induced apoptosis in dorsal root ganglion neurons.1 It penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration, ameliorating brain damage in a gerbil model of global ischemia.2 Displays neuroprotective effects in neurotrama rodent models.3 Calpain I Ki = 8 nM; Cathepsin B Ki = 24 nM in isolated enzyme assays. IC50 = 0.3 µM in intact cell assay.4
CAS Number: 88191-84-8
Manufacturer Part Number/SKU: 10-3005-25mg-EA
Tags: Focus Biomolecules