MAC-545496, GraR inhibitor, 25mg, CAS# 838810-96-1
$195.00
N-[(5-Chloropyridin-2-yl)carbamothioyl]-3-nitro-4-piperidin-1-ylbenzamide Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3951-25mg-EA
MAC-545496, GraR inhibitor, 25mg, CAS# 838810-96-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibitor of glycopeptide-resistance-associated protein R (GraR, also known as ApsR). GraR and its regulatory system are important for virulence of S. aureus. MAC-545496 is able to reverse ß-lactam resistance in S. aureus in a G. Mellonella larvae model. 0.06 µg/mL MAC-545496 lowered the minimum inhibitory concentration (MIC) for oxacillin against S. aureus below the CLSI clinical breakpoint. It lowered the ß-lactam MIC from 512 to 8 µg/mL against S. aureus USA300.
CAS Number: 838810-96-1
Manufacturer Part Number/SKU: 10-3951-25mg-EA
Tags: Focus Biomolecules