Manufacturer: Focus Biomolecules
Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.
CAS Number: 396129-53-6
Manufacturer Part Number/SKU: 10-1492-25mg-EA
Tags: Focus Biomolecules