Locostatin, RKIP/Raf-1 kinase disruptor, 5mg, CAS# 133812-16-5
$48.00
(4S)-3-[(E)-But-2-enoyl]-4-benzyl-2-oxazolidinone Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5381-5mg-EA
Locostatin, RKIP/Raf-1 kinase disruptor, 5mg, CAS# 133812-16-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibits cell migration by disrupting the interaction between Raf kinase inhibitor protein (RKIP) and Raf-1 kinase.1 Locostatin covalently binds to His86 of RKIP and also disrupts its interaction with G protein-coupled receptor kinase 2.2 Effectively inhibits cytokine release by human lymphocytes.3 Alleviates CCl4-induced liver fibrosis in a mouse model.4 A useful probe to explore the complex functions of RKIP in cell physiology.5
CAS Number: 133812-16-5
Manufacturer Part Number/SKU: 10-5381-5mg-EA
Tags: Focus Biomolecules