Lipofermata, Fatty acid transport protein 2 (FATP2) inhibitor, 10mg, CAS# 297180-15-5
$65.00
5-Bromo-5’phenylspiro[1H-indole-3,2’-3H-1,3,4-thiadiazole]-2-one; Purity: 98% Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3902-10mg-EA
Lipofermata, Fatty acid transport protein 2 (FATP2) inhibitor, 10mg, CAS# 297180-15-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsLipofermata is an inhibitor of fatty acid transport protein 2 (FATP2; IC50 = 4.84 µM).1 It does not inhibit glucose transport or the activity of long chain acyl-CoA synthetase. It prevented palmitate-mediated oxidative stress, induction of BiP and CHOP, and cell death in a dose-dependent manner in hsHepG2 and mINS-1E cells suggesting utility in preventing fatty acid-mediated cell death pathways and lipotoxic disease.2 Inhibition was specific for long and very long chain fatty acids but not medium (C6-C10) acids. Lipofermata abrogates lipid transport into melanoma cells and reduces melanoma growth and invasion.3
CAS Number: 297180-15-5
Manufacturer Part Number/SKU: 10-3902-10mg-EA
Tags: Focus Biomolecules