Lapatinib_base, EGFR and HER2 inhibitor, 50mg, CAS# 231277-92-2

Lapatinib_base, EGFR and HER2 inhibitor, 50mg, CAS# 231277-92-2

Lenalidomide, Immunomodulator, 500mg, CAS# 191732-72-6

Lenalidomide, Immunomodulator, 500mg, CAS# 191732-72-6

Lenalidomide, Immunomodulator, 100mg, CAS# 191732-72-6

$75.00
(R,S)-3-(4-Amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione Purity: 98% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-2148-100mg-EA
Lenalidomide, Immunomodulator, 100mg, CAS# 191732-72-6 is available to buy in increments of 1

Product Details

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Thalidomide analog which, like thalidomide,1 binds to cereblon which is the substrate recognition component of a cullin-dependent ubiquitin ligase and inhibits its autoubiquitination activity2. Induces degradation of T-cell repressors Ikaros (IKZF1) and Aiolos (IKZF3) leading to T cell activation2. Selective inhibition of IKZF1 and IKZF3 in multiple myeloma cells results in cell death3,4. Cell permeable. Caution: Teratogenic

CAS Number: 191732-72-6

Manufacturer Part Number/SKU: 10-2148-100mg-EA

Tags: Focus Biomolecules