L524-0366, Fn14 antagonist, 5mg, CAS# 951612-19-4
$65.00
(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)(thiomorpholino)methanone Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1536-5mg-EA
L524-0366, Fn14 antagonist, 5mg, CAS# 951612-19-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsFn14 antagonist. Competes with TNF-like weak inducer of apoptosis (TWEAK) C-terminal/extracellular TNF homology domain (THD) for Fn14 binding (KD = 7.12 µM). It specifically inhibits TWEAK-Fn14-mediated NFκB activation. It completely suppressed TWEAK-induced T98G cell migration (10 μM) without cytotoxicity up to 50 μM1. L524-0366 is the first compound known to interfere with the TWEAK/Fn14 inter-action and may serve as a lead compound for the development of new therapeutics2.
CAS Number: 951612-19-4
Manufacturer Part Number/SKU: 10-1536-5mg-EA
Tags: Focus Biomolecules