L-Buthionine Sulfoximine, GCL inhibitor, 100mg, CAS# 83730-53-4
$50.00
2(S)-Amino-4-(S-butylsulfonimidoyl)butanoic acid Purity: >98% Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4572-100mg-EA
L-Buthionine Sulfoximine, GCL inhibitor, 100mg, CAS# 83730-53-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsButhionine sulfoximine is an irreversible inhibitor of γ-glutamylcysteine ligase (GCL). GCL is the first enzyme of the cellular glutathione biosynthetic pathway. Dysregulation of glutathione homeostasis is involved in many diseases including cancer, diabetes, neurodegenerative disorders and HIV/AIDS.1 Most disease states involve decreased glutathione synthesis, however, in cancer, it is increased supporting cellular proliferation and protecting cancer cells. Pharmacological inhibition of GCL has been examined as a potential cancer treatment.2-4
CAS Number: 83730-53-4
Manufacturer Part Number/SKU: 10-4572-100mg-EA
Tags: Focus Biomolecules