KU-55933, ATM Kinase inhibitor, 25mg, CAS# 587871-26-9
$260.00
2-(4-Morpholinyl)-6-(1-thiamthrenyl)-4H-pyran-4-one Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1518-25mg-EA
KU-55933, ATM Kinase inhibitor, 25mg, CAS# 587871-26-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective ATM kinase inhibitor IC50s= 13, 2500, 9300, 16600, >100000 and >100000 nM for ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively.1 Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21CIP1 levels in vitro.2 Disruption of ATM signaling in primary A-T fibroblasts leads to dysregulation of ribonucleotide reductase and increase resistance to inhibitors of mitochondrial respiration and translation.3 Sensitizes radio-resistant cancer cells.4 Provides neuroprotection against H2O2-induced cell damage.5
CAS Number: 587871-26-9
Manufacturer Part Number/SKU: 10-1518-25mg-EA
Tags: Focus Biomolecules