Manufacturer: Focus Biomolecules
KL101 is an isoform-selective stabilizer of the circadian clock protein CRY1. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. KL101 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.
CAS Number: 396721-89-4
Manufacturer Part Number/SKU: 10-3907-5mg-EA
Tags: Focus Biomolecules