Kifunensine, Mannosidase inhibitor, 5mg, CAS# 109944-15-2
$184.00
(5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2860-5mg-EA
Kifunensine, Mannosidase inhibitor, 5mg, CAS# 109944-15-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsHistorically isolated from Kitasatosporia kifunensee.1 Inhibitor of class I α-mannosidases which inhibit glycoprotein processing. Inhibits human endoplasmic reticulum α-1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with Ki values of 130 and 23 nM respectively.2 Inhibition of endoplasmic reticulum α-mannosidase I activity rescues the human α-sarcoglycan R77C mutation suggesting a new pharmacological approach for limb girdle muscular dystrophy type 2D patients carrying mutations that impair α-sarcoglycan trafficking.3 Improves maturation of misfolded proteins.4
CAS Number: 109944-15-2
Manufacturer Part Number/SKU: 10-2860-5mg-EA
Tags: Focus Biomolecules