Ki8751, VEGFR2 inhibitor, 5mg, CAS# 228559-41-9
$39.00
N-(2,4-Difluorophenyl)-N’-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4388-5mg-EA
Ki8751, VEGFR2 inhibitor, 5mg, CAS# 228559-41-9 is available to buy in increments of 1
Product Details
Very potent (IC50 = 0.9 nM) inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2).1 It also inhibited PDGFRα (IC50 = 67 nM), c-Kit (IC50 = 40 nM), and FGFR2 (IC50 = 170 nM). Ki8751 completely suppressed HUVEC growth at 1 nM. Ki8751 completely inhibited tumor growth in LC-6 human tumor xenografts @ 5mg/kg. Ki8751 displayed anti-influenza A and B activity via disruption of virus entry in a PDGFRß/GM3-dependent manner.2
CAS Number: 228559-41-9
Manufacturer Part Number/SKU: 10-4388-5mg-EA
Tags: Focus Biomolecules