KB-R7943_mesylate, TRPC channel blocker, 50mg, CAS# 182004-65-5
$260.00
2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothioures mesylate Purity: 98% by TLC [ 10% methanol in methylene chloride + 0.1% NH4OH; Rf = 0.40] NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1163-50mg-EA
KB-R7943_mesylate, TRPC channel blocker, 50mg, CAS# 182004-65-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsKB-R7943 is a potent and selective inhibitor of the reversed Na+/Ca2+ exchanger (NCE or NCX; IC50's = 1.2-2.4 µM in cardiomyocytes, smooth muscle cells, NCX1-transfected fibroblasts1; 0.7µM in cultured rat forebrain2). KB-R7943 has also been shown to inhibit the mitochondrial Ca2+ uniporter (MCU) - Ki = 5.5 µM.3 Recently shown to inhibit complex I in the mitochondrial respiratory chain (IC50 = 11.4 µM) and block NMDA receptors (IC50 = 13.4 µM).4
CAS Number: 182004-65-5
Manufacturer Part Number/SKU: 10-1163-50mg-EA
Tags: Focus Biomolecules