JNK-IN-8, JNK inhibitor, 25mg, CAS# 1410880-22-6
$200.00
3-[[4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4780-25mg-EA
JNK-IN-8, JNK inhibitor, 25mg, CAS# 1410880-22-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsJNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively).1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cognitive impairment by inhibition of JNK/NF-kB-mediated NLRP3 inflammasome activation.3
CAS Number: 1410880-22-6
Manufacturer Part Number/SKU: 10-4780-25mg-EA
Tags: Focus Biomolecules