ISRIB, Integrated stress response inhibitor, 5mg, CAS# 1597403-47-8
$60.00
N.N’-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1539-5mg-EA
ISRIB, Integrated stress response inhibitor, 5mg, CAS# 1597403-47-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsIntegrated stress response inhibitor. Potently reverses the effects of initiation factor 2α (eIF2α) phosphorylation, IC50=5 nM.1 Enhances spatial and fear-associated learning in mice and enhances cognitive function.1,2 Mechanism of action involves activation of eiF2β.3 Suppresses ER stress-induced inflammatory gene expression.4 Potently attenuates amyloid β-induced neuronal cell death (12.5-25 nM) with no effect on amyloid β production.5 Reverses hippocampal-dependent cognitive deficits induced by traumatic brain injury in two different injury mouse models.6
CAS Number: 1597403-47-8
Manufacturer Part Number/SKU: 10-1539-5mg-EA
Tags: Focus Biomolecules