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IPA-3, PAK1 inhibitor, 50mg, CAS# 42521-82-4

$240.00
1,1'-Dithiodi-2-naphthol Purity: 98% by TLC (methylene chloride; Rf=0.75) NMr (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4765-50mg-EA
IPA-3, PAK1 inhibitor, 50mg, CAS# 42521-82-4 is available to buy in increments of 1

Product Details

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IPA-3 is a selective allosteric inhibitor of Group 1 p21-activated kinase (PAK1 IC50 = 2.5 µM)1 via covalent binding to the PAK1 regulatory domain preventing binding to the upstream activator Cdc422. IPA-3 has been shown to induce cell death in human leukemic cell lines3, significantly inhibit TGFβ1-induced prostate cell epithelial to mesenchymal transition4 and inhibits the growth of liver cancer cells5.

CAS Number: 42521-82-4

Manufacturer Part Number/SKU: 10-4765-50mg-EA

Tags: Focus Biomolecules