Ionomycin, Calcium ionophore, 1mg, CAS# 56092-81-0
$48.00
Fermentation product from Streptomyces conglobatus Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2079-1mg-EA
Ionomycin, Calcium ionophore, 1mg, CAS# 56092-81-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsHighly selective nonfluorescent calcium (Ca2+) ionophore.1 Induces a rapid rise in cytosolic Ca2+ in human neutrophils which is due to both release from cytosolic Ca2+ stores as well as Ca2+ influx.2 It activates (2 μM) and primes (20-200 nM) neutrophil NADPH oxidase2. Down regulates beta-catenin/Tcf signaling in a colon cancer cell line via suppressing the binding of Tcf to its specific DNA-binding site.3 In rat hepatoma cells, sub-lethal ionomycin activates the stress response by activating SAPK/JNK and HSF/HSE interaction leading to upregulation of HSP70 biosynthesis.4
CAS Number: 56092-81-0
Manufacturer Part Number/SKU: 10-2079-1mg-EA
Tags: Focus Biomolecules