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gamma-L-Glutamyl-p-nitroanilide_HCl, L-glutamine uptake inhibitor and γ-glutamyl transpeptidase substrate, 250mg, CAS# 67953-08-6

gamma-L-Glutamyl-p-nitroanilide_HCl, L-glutamine uptake inhibitor and γ-glutamyl transpeptidase substrate, 250mg, CAS# 67953-08-6

L-Buthionine Sulfoximine, GCL inhibitor, 100mg, CAS# 83730-53-4

L-Buthionine Sulfoximine, GCL inhibitor, 100mg, CAS# 83730-53-4

Indoximod, IDO modulator / tryptophan mimetic, 50mg, CAS# 110117-83-4

$35.00
1-Methyl-D-tryptophan Purity: >98% Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4569-50mg-EA
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Indoximod, IDO modulator / tryptophan mimetic, 50mg, CAS# 110117-83-4 is available to buy in increments of 1

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Indoximod is a modulator of indoleamine 2,3-dioxygenase (IDO) activity.1 IDO can be used by tumors to avoid elimination by the host immune response2,3, thus inhibition of IDO is an interesting cancer therapeutic option. Indoximod is not a direct inhibitor of IDO, but instead targets the IDO gene leading to downstream effects.3 IDO-mediated catabolism of tryptophan inhibits the immunoregulatory kinases mTOR and PKC5. This is relieved by Indoximod acting as a potent tryptophan mimetic restoring mTOR and PKC signaling.4

CAS Number: 110117-83-4

Manufacturer Part Number/SKU: 10-4569-50mg-EA

Tags: Focus Biomolecules