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Indacaterol maleate, ß2 adrenoceptor agonist/Splicing factor SRSF6 inhibitor, 10mg, CAS# 753498-25-8

$40.00
5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one maleate salt Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4371-10mg-EA
Indacaterol maleate, ß2 adrenoceptor agonist/Splicing factor SRSF6 inhibitor, 10mg, CAS# 753498-25-8 is available to buy in increments of 1

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Indacaterol maleate is a full agonist (pEC50 = 8.06) of the human ß2 adrenoceptor.1,2 Clinically important drug for the treatment of chronic obstructive pulmonary disease. Indacaterol blocked colorectal cancer progression in vitro (IC50 = 19.01 µM) and in vivo via inhibition of the splicing factor SRSF6 by binding to its RRM2 domain.3 It also blocked cell migration in metastatic breast cancer MDA-MB-231 cells by a similar mechanism.4

CAS Number: 753498-25-8

Manufacturer Part Number/SKU: 10-4371-10mg-EA

Tags: Focus Biomolecules