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Importazole, Blocks importin-b-mediated nuclear import, 5mg, CAS# 662163-81-7

$50.00
N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine Purity: 97% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-1412-5mg-EA
Importazole, Blocks importin-b-mediated nuclear import, 5mg, CAS# 662163-81-7 is available to buy in increments of 1

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Specifically inhibits importin-β-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export1. When added to cells during mitosis it impairs the release of an importin-b cargo probe and causes defects in spindle assembly. Inhibition of importin-β function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-b/RanGTP pathway2-4. Cell permeable

CAS Number: 662163-81-7

Manufacturer Part Number/SKU: 10-1412-5mg-EA

Tags: Focus Biomolecules