Manufacturer: Focus Biomolecules
Specifically inhibits importin-β-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export1. When added to cells during mitosis it impairs the release of an importin-b cargo probe and causes defects in spindle assembly. Inhibition of importin-β function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-b/RanGTP pathway2-4. Cell permeable
CAS Number: 662163-81-7
Manufacturer Part Number/SKU: 10-1412-5mg-EA
Tags: Focus Biomolecules