Ibudilast, Neuroinflammation inhibitor (PDE pan-inhibitor), 5mg, CAS# 50847-11-5
$40.00
3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine Purity: 98% by HPLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2236-5mg-EA
Ibudilast, Neuroinflammation inhibitor (PDE pan-inhibitor), 5mg, CAS# 50847-11-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPhosphodiesterase inhibitor with some selectivity for PDE4 and 5. (IC50s= 53, 35, 48,12 and10 μM for PDE 1a, 2, 3, 4 and 5 respectively1). Acts as a cerebral vasodilator by selectively inducing a cGMP-independent relaxation of the intracranial vertebrobasilar artery.2 Attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma via PKA signaling.3 A glial cell activation inhibitor.4 Enhances morphine analgesia and attenuates tolerance and withdrawaI.5 Orally active and crosses the blood-brain barrier.5
CAS Number: 50847-11-5
Manufacturer Part Number/SKU: 10-2236-5mg-EA
Tags: Focus Biomolecules