I-BET762, BET bromodomain inhibitor / Supresses Myc transcription, 5mg, CAS# 1260907-17-2
$80.00
(4S)- 6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4122-5mg-EA
I-BET762, BET bromodomain inhibitor / Supresses Myc transcription, 5mg, CAS# 1260907-17-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsI-BET762 is a potent inhibitor of the BET family of bromodomains with no activity at bromodomains BAZ2B, SP140, ATAD2, CREBBO, and PCAF.1,2 IC50's for H4Ac peptide displacement: BRD2 = 32.5nM, BRD3 = 42.4nM, BRD4 = 36.1nM.1 It was able to suppress proinflammatory proteins by macrophage, block acute inflammation in mice1, and suppressed the inflammatory function of T cells3. Inhibition of BET bromodomains results in downregulation of Myc transcription, an important oncogene.4
CAS Number: 1260907-17-2
Manufacturer Part Number/SKU: 10-4122-5mg-EA
Tags: Focus Biomolecules