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HTS01037, FABP inhibitor, 25mg, CAS# 682741-29-3

$240.00
4-[(3-Carboxy-1-oxo-2-propen-1-yl)amino]-[2,2’-bithiophene]-5-carboxylic acid Purity: 5-methyl ester Purity: 98% by HPLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-1453-25mg-EA
HTS01037, FABP inhibitor, 25mg, CAS# 682741-29-3 is available to buy in increments of 1

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Inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARγ in macrophages1. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis2. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress3. Reduces LPS-stimulated IL-1β secretion in a mouse model4. Inhibits VLDL-induced foam cell formation5.

CAS Number: 682741-29-3

Manufacturer Part Number/SKU: 10-1453-25mg-EA

Tags: Focus Biomolecules