HET0016, 20-HETE biosynthesis inhibitor, 25mg, CAS# 339068-25-6
$275.00
N-Hydroxy-N’-(4-butyl-2-methylphenyl)formamidine Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5246-25mg-EA
HET0016, 20-HETE biosynthesis inhibitor, 25mg, CAS# 339068-25-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsHET0016 (339068-25-6) inhibits 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis via omega oxidation of arachidonic acid mediated by CYP4A and 4F (IC50=8.9 nM in human renal microsomes).1 It displays neuroprotective effects in a rat model of traumatic brain injury via inhibition of neuronal pyroptosis.2 HET0016 attenuates cerebral ischemia-reperfusion injury3 as well as oxidative injury and peripheral nerve damage in type-2 diabetic mice4. It alleviates myocardial oxidative stress5 and restores endothelial function suggesting therapeutic potential in obesity-associated vascular disease6.
CAS Number: 339068-25-6
Manufacturer Part Number/SKU: 10-5246-25mg-EA
Tags: Focus Biomolecules