GW788388, TGF-ß receptor kinase inhibitor, 25mg, CAS# 452342-67-5
$260.00
4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5521-25mg-EA
GW788388, TGF-ß receptor kinase inhibitor, 25mg, CAS# 452342-67-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent inhibitor of TGF-β receptor kinases ALK4, ALK5 (IC50=18 nM), ALK7, and TGFβRII, but not BMP type II receptor kinase.1,2 Blocks TGF-β-mediated signaling, including collagen type I and VEGF, in turn reducing fibrosis and angiogenesis in various mouse models.3,4 GW788388 attenuates TGF-β-induced epithelial to mesenchymal transition (EMT) in human peritoneal mesothelial cells.5
CAS Number: 452342-67-5
Manufacturer Part Number/SKU: 10-5521-25mg-EA
Tags: Focus Biomolecules