Manufacturer: Focus Biomolecules
GSK872 is a potent (IC50 = 1.8nM domain binding; IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3).1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce Caspase8-mediated apoptosis at higher concentrations (e.g.3 µM).2
CAS Number: 1346546-69-7
Manufacturer Part Number/SKU: 10-4861-25mg-EA
Tags: Focus Biomolecules