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GSK8612, Highly selective TBK1 inhibitor, 25mg, CAS# 2361659-62-1

$255.00
4-[[[5-Bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4693-25mg-EA
GSK8612, Highly selective TBK1 inhibitor, 25mg, CAS# 2361659-62-1 is available to buy in increments of 1

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Highly selective and potent (avg. pIC50 = 6.8 versus recombinant TBK1) inhibitor of Tank-binding Kinase-1 (TBK1) with higher affinity for unactivated TBK1. It inhibited phosphorylation of IRF3 (pIC50 = 6.0), inhibited the release of IFNa from human PBMC's (pIC50 = 6.1), and inhibited IFNb secretion from THP-1 cells (pIC50 = 5.8 dsDNA virus, 6.3 cGAMP stilmulated cells).

CAS Number: 2361659-62-1

Manufacturer Part Number/SKU: 10-4693-25mg-EA

Tags: Focus Biomolecules