GSK583, RIP2 kinase inhibitor, 10mg, CAS# 1346547-00-9
$40.00
6-tert-Butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinoline-4-amine Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4761-10mg-EA
GSK583, RIP2 kinase inhibitor, 10mg, CAS# 1346547-00-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsGSK583 is a highly selective and potent inhibitor of RIP2 kinase, IC50 = 5 nM human and IC50 = 2 nM rat.1 It also potently Inhibits isolated RPI3 kinase (IC50 = 5 nM) but is inactive against RIP3 in cellular assays due to a very low KM,ATP. GSK583 blocks NOD2 signaling by interfering with XIAP-RIP2 binding resulting in decreased cytokine and chemokine production.1,2
CAS Number: 1346547-00-9
Manufacturer Part Number/SKU: 10-4761-10mg-EA
Tags: Focus Biomolecules