GSK-J4, JMJ H3K27 Demethylase inhibitor (Cell Permeable), 25mg, CAS# 1373423-53-0
$160.00
N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-ß-alanine ethyl ester Purity: 99% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1394-25mg-EA
GSK-J4, JMJ H3K27 Demethylase inhibitor (Cell Permeable), 25mg, CAS# 1373423-53-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsHistone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 μM for the inhibition of TNFα release). Cell permeable, ethyl ester of GSK J11. Rescues newborn pups from embryonic lethality in BRAF knockin mice which recapitulate major features of RASopathies2.
CAS Number: 1373423-53-0
Manufacturer Part Number/SKU: 10-1394-25mg-EA
Tags: Focus Biomolecules