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GSK-J1, JMJ H3K27 Demethylase inhibitor (Non-cell permeable), 25mg, CAS# 1373422-53-7

$300.00
N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-ß-alanine Purity: 99% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-1393-25mg-EA
GSK-J1, JMJ H3K27 Demethylase inhibitor (Non-cell permeable), 25mg, CAS# 1373422-53-7 is available to buy in increments of 1

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Potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and as such is useful as a standard in in vitro assays. A cell permeable ethyl ester analog is also available.

CAS Number: 1373422-53-7

Manufacturer Part Number/SKU: 10-1393-25mg-EA

Tags: Focus Biomolecules