GSK-1702934A, TRPC3/6 activator, 5mg, CAS# 924377-85-5
$60.00
1-(1-(5,6,7,8-Tetrahydro=4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl)-1H-benzo[d]- imidazole-2(3H)-one Purity: 98% by TLC (5% CH3OH in CH2Cl2 Rf=0.34) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1445-5mg-EA
GSK-1702934A, TRPC3/6 activator, 5mg, CAS# 924377-85-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsTRPC3 activator. In whole-cell patch-clamp experiments in HEK293 cells transduced with recombinant human TRPC3 or TRPC6, GSK-1702934A activated the TRPC3 and TRPC6 current with EC50 of 0.08 μM and 0.44 μM respectively. In the rat cardiomyocyte-like cell line H9C2 GSK-1702934A (1μM) activated TRPC6-like current and was completely blocked by GSK-417651A. It transiently increased the perfusion pressure of isolated rat heart retrogradely perfused via aortic cannulation at 1μM.1 Induces pro-arrhythmic and inotropic effects in TRPC3-overexpressing monocytes.2
CAS Number: 924377-85-5
Manufacturer Part Number/SKU: 10-1445-5mg-EA
Tags: Focus Biomolecules