Ganetespib, HSP90 inhibitor, 25mg, CAS# 888216-25-9
$225.00
3-(2,4-Dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4474-25mg-EA
Ganetespib, HSP90 inhibitor, 25mg, CAS# 888216-25-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsGanetespib is an inhibitor of heat shock protein 90 (IC50 = 19 nM, canine C2 malignant mast cells; 4 nM, canine BR malignant mast cells) binding to the N-terminal ATP site.1 It displayed potent cytotoxicity against a panel of 57 transformed cell lines of both hematologic and solid tumors with IC50's between 14 and 280 nM.2 Ganetespib enhanced T-cell-mediated killing of human melanoma cells and potentiated responses to anti-CTLA4 and anti-PD1 therapy via upregulation of interferon response genes.3 In multiple clinical trials for various cancers.
CAS Number: 888216-25-9
Manufacturer Part Number/SKU: 10-4474-25mg-EA
Tags: Focus Biomolecules