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Fumarate hydratase-IN-1, Fumarate hydratase inhibitor, 5mg, CAS# 1644060-37-6

$70.00
Ethyl rel-(3S,3aR)-3-[2-(Methylamino)-2-oxoethyl]-2-oxo-1-[(4-phenylphenyl)methyl]-3,4,5,6-tetrahydroindole-3a-carboxylate Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4578-5mg-EA
Fumarate hydratase-IN-1, Fumarate hydratase inhibitor, 5mg, CAS# 1644060-37-6 is available to buy in increments of 1

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Fumarate hydratase-IN-1 is a pro-drug inhibitor of fumarate hydratase, an important enzyme in the tricarboxylic acid (TCA) cycle. This cell permeable compound is converted to the active carboxylic acid by intracellular esterases (Ki = 4.5 µM for free acid). The ethyl ester displayed cell-growth inhibitory activity against several cancer lines under nutrient (glucose) deprived conditions with an average IC50 = 2.2 µM.

CAS Number: 1644060-37-6

Manufacturer Part Number/SKU: 10-4578-5mg-EA

Tags: Focus Biomolecules