FQI1, LSF inhibitor, 25mg, CAS# 599151-35-6
$280.00
8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-6(5H)-one Purity: 98% by TLC NMR (conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1360-25mg-EA
FQI1, LSF inhibitor, 25mg, CAS# 599151-35-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 mM). Rapidly induces apoptosis in an aggressive hepatocellular carcinoma (HCC) cell line and dramatically inhibits tumor growth in a mouse xenograft model with no general tissue cytotoxicity.1,2 In human HCC cells, FQI1 induced mitotic arrest with an accompanying increase in cyclin B1.3 Blocks LSF-stimulated activation of DNA methyltransferase 1.4 Cell permeable.
CAS Number: 599151-35-6
Manufacturer Part Number/SKU: 10-1360-25mg-EA
Tags: Focus Biomolecules